Hours Of Operations Lowe's Home Improvement South Carolina Hartsville Lowe's Home Improvement Hours of Operation and Locations in Hartsville, SC 4.8 - 142 votes 1 Locations in Hartsville www.lowes.com Lowe's Home Improvement Hours Category: Home & Garden Lowe's Home Improvement - Hartsville, SC 29550 819 S 4th St(843) 339-2501 View Store Details Explore HartsvilleView More Apparel Big LotsGoody'sCatoH & MCarhartt Sports Sports Time Jewelry CatoBelk Recommend For You Lower Corner Soccer Store Lucky Dollar Lucky Supermarket Luis Garage Doors & Gates Lupita Grocery LYNX-USA Incorporated M & G Variety Store M & M Grocery Madison Industries Incorporated Magic Clean Carpet