Hours Of Operations Lowe's Home Improvement Virginia Wytheville Lowe's Home Improvement Hours of Operation and Locations in Wytheville, VA 4.8 - 142 votes 1 Locations in Wytheville www.lowes.com Lowe's Home Improvement Hours Category: Home & Garden Lowe's Home Improvement - Wytheville, VA 24382 185 Dominion St(276) 223-9880 View Store Details Explore WythevilleView More Apparel KmartGoody'sPeeblesCarharttCarter's Sports Coleman Jewelry Penelope Recommend For You Lower Corner Soccer Store Lucky Dollar Lucky Supermarket Luis Garage Doors & Gates Lupita Grocery LYNX-USA Incorporated M & G Variety Store M & M Grocery Madison Industries Incorporated Magic Clean Carpet